{"id":238828,"date":"2021-10-18T09:00:00","date_gmt":"2021-10-18T08:00:00","guid":{"rendered":"https:\/\/eu.intelligentlabs.org\/ako-si-zvysit-citlivost-na-inzulin\/"},"modified":"2021-10-18T09:00:00","modified_gmt":"2021-10-18T08:00:00","slug":"ako-si-zvysit-citlivost-na-inzulin","status":"publish","type":"post","link":"https:\/\/eu.intelligentlabs.org\/sk-sk\/ako-si-zvysit-citlivost-na-inzulin\/","title":{"rendered":"Ako si prirodzene zv\u00fd\u0161i\u0165 citlivos\u0165 na inzul\u00edn"},"content":{"rendered":"\n

V poslednej dobe nie je mo\u017en\u00e9 po\u010d\u00fava\u0165 r\u00e1dio alebo listova\u0165 \u010dasopisom bez toho, aby ste nepo\u010duli, ako niekto hovor\u00ed o obezite a cukrovke 2. typu. Rezistencia na inzul\u00edn je jednou z aktu\u00e1lnych t\u00e9m s\u00fa\u010dasnosti a jednou z najv\u00e4\u010d\u0161\u00edch v\u00fdziev pre na\u0161e zdravie. Je to takisto hlavn\u00e1 pr\u00ed\u010dina cukrovky, vysokej hladiny tukov v krvi a hypertenzie.<\/p>\n\n\n\n

Dobrou spr\u00e1vou je, \u017ee existuje naozaj ve\u013ea vec\u00ed, ktor\u00e9 m\u00f4\u017eeme urobi\u0165, aby sme si pomohli aj my sami. Chronick\u00e9 choroby nemusia by\u0165 na\u0161\u00edm osudom. \u00dapravou na\u0161ej stravy, zaraden\u00edm cvi\u010denia do denn\u00e9ho re\u017eimu a \u017eivotn\u00e9ho \u0161t\u00fdlu m\u00f4\u017eeme prirodzene zv\u00fd\u0161i\u0165 citlivos\u0165 na inzul\u00edn a zosta\u0165 fit, kedyko\u013evek si len zmysl\u00edme. A \u010do viac, niektor\u00e9 zmeny m\u00f4\u017eu by\u0165 dokonca z\u00e1bavn\u00e9. Pre\u010d\u00edtajte si n\u00e1\u0161 n\u00e1vod, ako prirodzene zv\u00fd\u0161i\u0165 citlivos\u0165 na inzul\u00edn.<\/p>\n\n\n\n

1) Obmedzte sacharidy<\/strong><\/h2>\n\n\n\n

Inzul\u00edn sa uvo\u013e\u0148uje, ke\u010f jeme uh\u013eohydr\u00e1ty, zn\u00e1me aj ako sacharidy. V\u010faka rafinovan\u00e9mu cukru je n\u00e1rast inzul\u00ednu vy\u0161\u0161\u00ed ako pri komplexn\u00fdch sacharidoch, ale pravdou je, \u017ee celkovo zn\u00ed\u017een\u00edm pr\u00edjmu uh\u013eohydr\u00e1tov dosiahneme ni\u017e\u0161iu produkciu inzul\u00ednu.<\/p>\n\n\n\n

Preto\u017ee inzul\u00edn pom\u00e1ha uklada\u0165 tuk, menej cirkuluj\u00faceho inzul\u00ednu v organizme m\u00f4\u017ee zabr\u00e1ni\u0165 priberaniu na v\u00e1he, obmedzi\u0165 tento ne\u017eiaduci efekt alebo ho dokonca aj zvr\u00e1ti\u0165. Bielkoviny a tuky s\u00fa tie\u017e pomerne s\u00fdte, tak\u017ee \u013eudia s n\u00edzkosacharidovou di\u00e9tou b\u00fdvaj\u00fa menej hladn\u00ed a prirodzene jedia menej kal\u00f3ri\u00ed. Jednoducho povedan\u00e9, n\u00edzkosacharidov\u00e1 di\u00e9ta (1<\/a>) v\u00e1m pom\u00f4\u017ee schudn\u00fa\u0165 a zlep\u0161i\u0165 citlivos\u0165 na inzul\u00edn.<\/p>\n\n\n\n

Vyl\u00fa\u010dte teda v\u0161etok rafinovan\u00fd cukor a biele sacharidy, dokonca aj redukcia u\u017e miernych mno\u017estiev m\u00f4\u017eu zn\u00ed\u017ei\u0165 citlivos\u0165 na inzul\u00edn (2<\/a>). Netla\u010dte v\u0161ak na p\u00edlu a\u017e pr\u00edli\u0161; z\u00edskavajte komplexn\u00e9 sacharidy z ve\u013ek\u00e9ho mno\u017estva zeleniny a bobu\u013eov\u00edn, orechov a semien. Ak sa dostanete do stavu ket\u00f3zy<\/a>, kedy sa va\u0161e telo prisp\u00f4sob\u00ed spa\u013eovaniu tukov namiesto gluk\u00f3zy ako paliva, va\u0161e tkaniv\u00e1 si m\u00f4\u017eu a dok\u00e1\u017eu vyvin\u00fa\u0165 ur\u010dit\u00fd stupe\u0148 inzul\u00ednovej rezistencie ako ochrann\u00fd mechanizmus, ktor\u00fd u\u0161etr\u00ed v\u0161etku gluk\u00f3zu pre mozog (3<\/a>).<\/p>\n\n\n\n

\"zvr\u00e1ti\u0165<\/figure>\n\n\n\n

2) Dv\u00edhajte \u0165a\u017ek\u00fa v\u00e1hu alebo HIITujte<\/strong><\/h2>\n\n\n\n

Cvi\u010denie m\u00f4\u017ee zv\u00fd\u0161i\u0165 citlivos\u0165 na inzul\u00edn, ale mus\u00edte to urobi\u0165 spr\u00e1vne. Dlh\u00e9 hodiny behania po chodn\u00edkoch alebo be\u017eiacom p\u00e1se m\u00f4\u017eu skuto\u010dne zv\u00fd\u0161i\u0165 sk\u00faste posil\u0148ova\u0165 s \u010dinkami alebo vysk\u00fa\u0161ajte intervalov\u00fd tr\u00e9ning s vysok\u00fdm za\u0165a\u017een\u00edm (HIIT<\/a>), aby ste zlep\u0161ili v\u00e1\u0161 metabolick\u00fd profil a tak aj cel\u00fd organizmus.<\/p>\n\n\n\n

Je to v\u0161etko sp\u00f4soben\u00e9 horm\u00f3nom, naz\u00fdvan\u00fdm kortizol. Kortizol m\u00e1 \u017eivotne d\u00f4le\u017eit\u00fa fyziologick\u00fa \u00falohu ako jeden zo stresov\u00fdch horm\u00f3nov v tele, pom\u00e1ha n\u00e1m be\u017ea\u0165 r\u00fdchlej\u0161ie a bojova\u0165 o v\u0161etko tvrd\u0161ie. Zni\u017euje v\u0161ak aj na\u0161u citlivos\u0165 na inzul\u00edn (4<\/a>), najm\u00e4 ak s\u00fa jeho hladiny dlhodobo vysok\u00e9. \u010cas a intenzita cvi\u010denia m\u00f4\u017eu ovplyvni\u0165 \u00farove\u0148 uvo\u013e\u0148ovania kortizolu. \u010co sa t\u00fdka cvi\u010denia, viac nemus\u00ed v\u017edy znamena\u0165 lep\u0161ie. Tr\u00e9ning, dlh\u0161\u00ed viac ako 60 min\u00fat, dokonca aj pri n\u00edzkej intenzite, spa\u013euje z\u00e1soby glykog\u00e9nu v tele a stimuluje uvo\u013e\u0148ovanie kortizolu. \u0160t\u00fadia (5<\/a>)  potvrdila, \u017ee dlhodob\u00e1 expoz\u00edcia kortizolu bola u vytrvalostn\u00fdch \u0161portovcov v\u00fdrazne vy\u0161\u0161ia.<\/p>\n\n\n\n

Kr\u00e1tke, vysoko intenz\u00edvne cvi\u010denia, ako s\u00fa \u0161printy, HIIT alebo silov\u00fd tr\u00e9ning, sp\u00f4sobuj\u00fa men\u0161ie zv\u00fd\u0161enie plazmatick\u00fdch koncentr\u00e1ci\u00ed kortizolu. Jeho hladiny v\u0161ak narastaj\u00fa, ak s\u00fa doby odpo\u010dinku kr\u00e1tke a \u00farove\u0148 nasadenia vysok\u00e1. To je obzvl\u00e1\u0161\u0165 d\u00f4le\u017eit\u00e9, ak cvi\u010d\u00edte, ke\u010f m\u00e1te hlad alebo trp\u00edte podv\u00fd\u017eivou. Zvy\u0161uje sa tie\u017e tr\u00e9ningom skoro r\u00e1no, ke\u010f s\u00fa hladiny kortizolu prirodzene vy\u0161\u0161ie (6<\/a>) and the response to exercise can be more. So a hard 6am workout before breakfast may actually be counterproductive for improving insulin sensitivity.<\/p>\n\n\n\n

(6) a reakcia organizmu na cvi\u010denie m\u00f4\u017ee by\u0165 \u00fa\u010dinnej\u0161ia. N\u00e1ro\u010dn\u00e9 cvi\u010denie o 6.00 r\u00e1no –  pred ra\u0148ajkami – m\u00f4\u017ee by\u0165 v skuto\u010dnosti kontraprodukt\u00edvne, ak je na\u0161\u00edm cie\u013eom zv\u00fd\u0161i\u0165 citlivos\u0165 na inzul\u00edn.<\/p>\n\n\n\n

\"cvi\u010denie<\/figure>\n\n\n\n

3) Zv\u00fd\u0161te si obsah Omega 3<\/strong><\/h2>\n\n\n\n

Existuje st\u00e1le viac a viac d\u00f4kazov, ktor\u00e9 nazna\u010duj\u00fa, \u017ee omega-3 v strave m\u00f4\u017ee by\u0165 jedn\u00fdm zo sp\u00f4sobov, ako m\u00f4\u017eeme zv\u00fd\u0161i\u0165 citlivos\u0165 na inzul\u00edn <\/a>a zn\u00ed\u017ei\u0165 v\u00fdskyt cukrovky 2. typu. Uk\u00e1zalo sa, \u017ee vy\u0161\u0161ie hladiny v strave alebo nameran\u00e9 v krvnom obehu skuto\u010dne znamenaj\u00fa rozdiel v aktu\u00e1lnom stave. Prvotn\u00e9 \u0161t\u00fadie uk\u00e1zali (7<\/a>), \u017ee doplnenie omega 3 z rybieho oleha m\u00f4\u017ee zlep\u0161i\u0165 vyu\u017eitie gluk\u00f3zy v tele a zn\u00ed\u017ei\u0165 inzul\u00ednov\u00fa rezistenciu (8<\/a>).<\/p>\n\n\n\n

Dopl\u0148te si teda do jed\u00e1lni\u010dka dostatok r\u00fdb a obzvl\u00e1\u0161\u0165 tu\u010dn\u00fdch druhov, aby hladina va\u0161ich omega 3 v organizme nar\u00e1stla. Makrela, sardinky, losos, tuniak a krab v\u00e1m zv\u00fd\u0161ia hladinu v tele, \u010di u\u017e s\u00fa mrazen\u00e9, \u010derstv\u00e9 alebo z plechovky. Aby ste z\u00edskali dostatok omega kysel\u00edn, budete musie\u0165 jes\u0165 ryby alebo in\u00e9 morsk\u00e9 plody najmenej 1 a\u017e 2 kr\u00e1t t\u00fd\u017edenne. V ide\u00e1lnom pr\u00edpade v\u0161ak jedzte morsk\u00e9 plody ka\u017ed\u00fd de\u0148, ak chcete vidie\u0165 a na vlastnej ko\u017ei poc\u00edti\u0165 rozdiel v citlivosti na inzul\u00edn; vyberajte si najm\u00e4 tmav\u00e9 tu\u010dn\u00e9 m\u00e4so, ktor\u00e9 je bohat\u0161ie na esenci\u00e1lne mastn\u00e9 kyseliny. Ak v\u00e1m nevo\u0148aj\u00fa morsk\u00e9 plody, potom za\u010dnite u\u017e\u00edva\u0165 v\u00fd\u017eivov\u00fd doplnok<\/a>, aby ste z\u00edskali v\u0161etky potrebn\u00e9 omega 3 kyseliny, bez nepr\u00edjemnej pachute rybiny.<\/p>\n\n\n\n

\"omega<\/figure>\n\n\n\n

4) Okore\u0148te si \u017eivot<\/strong><\/h2>\n\n\n\n

M\u00f4\u017ee to znie\u0165 prekvapivo, ale ak chcete vedie\u0165, ako zv\u00fd\u0161i\u0165 citlivos\u0165 na inzul\u00edn prirodzen\u00fdm sp\u00f4sobom, dodajte pokrmom, ktor\u00e9 jete, trocha chuti. V\u00fdskum (9<\/a>) ukazuje, \u017ee ak je va\u0161a inzul\u00ednov\u00e1 rezistencia vysok\u00e1 kv\u00f4li pr\u00edli\u0161 ve\u013ea neskor\u00fdch odchodom do postele a nedostatku sp\u00e1nku, potom \u0161korica m\u00f4\u017ee tento efekt dokonale zvr\u00e1ti\u0165. Len si ju nenasypte na z\u00e1kusky.<\/p>\n\n\n\n

Ak m\u00e1te rad\u0161ej nie\u010do pikantnej\u0161ie \u010di slan\u00e9, vysk\u00fa\u0161ajte vari\u0165 so z\u00e1zvorom, cesnakom a kurkumou (10,11<\/a>). U\u017eite si dokonale \u0161tip\u013eav\u00e9 kar\u00ed a m\u00f4\u017eete tak tie\u017e pom\u00f4c\u0165 zlep\u0161i\u0165 svoju toleranciu vo\u010di gluk\u00f3ze a senzibilizova\u0165 telo na p\u00f4sobenie inzul\u00ednu, \u010do je jednozna\u010dn\u00e1 v\u00fdhra v akejko\u013evek situ\u00e1cii.<\/p>\n\n\n\n

5) Vystavte sa slne\u010dn\u00fdm l\u00fa\u010dom (m\u00e1lo zn\u00e1my tip, ako prirodzene zv\u00fd\u0161i\u0165 citlivos\u0165 na inzul\u00edn)<\/strong><\/h2>\n\n\n\n

Na\u0161e tel\u00e1 si dok\u00e1\u017eu vytv\u00e1ra\u0165 vitam\u00edn D na slne\u010dnom svetle a \u010dasto je obsiahnut\u00fd aj v na\u0161ich potravin\u00e1ch. Napriek tomu pr\u00e1ca v kancel\u00e1ri\u00e1ch, nekone\u010dn\u00e9 sledovanie obrazoviek a konzol a nadmern\u00e9 pou\u017e\u00edvanie opa\u013eovac\u00edch kr\u00e9mov sp\u00f4sobilo, \u017ee mnoh\u00fdm z n\u00e1s ch\u00fdba pr\u00e1ve vitam\u00edn D.<\/p>\n\n\n\n

Rachit\u00edda m\u00f4\u017ee by\u0165 s\u00edce zriedkav\u00e1, ale pr\u00edli\u0161 m\u00e1lo vitam\u00ednu D m\u00f4\u017ee vies\u0165 k \u010fal\u0161\u00edm probl\u00e9mom. Vedci spojili n\u00edzke hladiny vitam\u00ednu D s inzul\u00ednovou rezistenciou a diabetom 2. typu. Podporte a zregenerujte hladinu trochou slne\u010dn\u00e9ho svitu, dostatkom tu\u010dn\u00fdch r\u00fdb, mlie\u010dnych v\u00fdrobkov a pe\u010dene. Zv\u00fd\u0161enie hladiny vitam\u00ednu D len prostredn\u00edctvom stravy m\u00f4\u017ee by\u0165 n\u00e1ro\u010dn\u00e9, preto zv\u00e1\u017ete aj denn\u00e9 u\u017e\u00edvanie v\u00fd\u017eivov\u00e9ho doplnku<\/a> (12<\/a>).<\/p>\n\n\n\n

\"vystavte<\/figure>\n\n\n\n

6) L\u00e1ska je to spr\u00e1vne rie\u0161enie<\/strong><\/h2>\n\n\n\n

Znie to pr\u00edli\u0161 dobre na to, aby to bola pravda? Verte tomu, preto\u017ee l\u00e1ska by v\u00e1s v skuto\u010dnosti dok\u00e1zala ochr\u00e1ni\u0165 pred cukrovkou. Zd\u00e1 sa, \u017ee tento \u00fa\u010dinok je spojen\u00fd s oxytoc\u00ednom – horm\u00f3nom, ktor\u00fd je spojen\u00fd s l\u00e1skou a telesn\u00fdm putom. Oxytoc\u00edn sa uvo\u013e\u0148uje, ke\u010f matka doj\u010d\u00ed svoje die\u0165a, ale na\u0161e hladiny takisto narastaj\u00fa, ak sa t\u00falime k milovanej osobe, sp\u00e1jame sa s niek\u00fdm  na spolo\u010denskej \u00farovni alebo dokonca hladk\u00e1me svojich psov. Existuje d\u00f4vod, pre\u010do je zn\u00e1my ako \u201ehorm\u00f3n maznania sa\u201c.<\/p>\n\n\n\n

Ak n\u00e1m je pod\u00e1van\u00fd oxytoc\u00edn, m\u00e1me tendenciu c\u00edti\u0165 sa pokojnej\u0161ie, \u0161\u0165astnej\u0161ie a bezpe\u010dnej\u0161ie. M\u00f4\u017ee to v\u0161ak ma\u0165 tie\u017e vplyv na na\u0161u reakciu na inzul\u00edn. \u0160t\u00fadia preuk\u00e1zala, \u017ee oxytoc\u00edn p\u00f4sobil na zvr\u00e1tenie inzul\u00ednovej rezistencie a zlep\u0161enie gluk\u00f3zovej tolerancie u ob\u00e9znych my\u0161\u00ed (13<\/a>). Mo\u017eno je l\u00e1ska skuto\u010dne droga.<\/p>\n\n\n\n

7) U\u017e\u00edvajte berber\u00edn<\/strong><\/h2>\n\n\n\n

N\u00e1\u0161 posledn\u00fd tip, ako prirodzene zv\u00fd\u0161i\u0165 citlivos\u0165 na inzul\u00edn, n\u00e1jdete v \u010dl\u00e1nku o berber\u00edne<\/a>. <\/p>\n\n\n\n

Berber\u00edn sa nach\u00e1dza v nieko\u013ek\u00fdch rastlin\u00e1ch a plodoch, vr\u00e1tane eur\u00f3pskych \u010du\u010doriedok, hrozna odordy Oregon, vodu\u013eke kanadskej, rastline goldthread, filodendr\u00f3ne a strome kurkumy. Berber\u00edn m\u00f4\u017ee zn\u00ed\u017ei\u0165 produkciu gluk\u00f3zy v pe\u010deni (14, 15<\/a>).<\/p>\n\n\n\n

Berber\u00edn m\u00e1 antibakteri\u00e1lne, protiz\u00e1palov\u00e9 a posil\u0148uj\u00face \u00fa\u010dinky. Uk\u00e1zalo sa tie\u017e, \u017ee dok\u00e1\u017ee zv\u00fd\u0161i\u0165 citlivos\u0165 na inzul\u00edn (16 \u2013 20<\/a>).<\/p>\n\n\n\n

A na z\u00e1ver (bonusov\u00fd tip)<\/strong><\/h2>\n\n\n\n

Ktor\u00fdko\u013evek z vy\u0161\u0161ie uveden\u00fdch tipov, ako prirodzene zv\u00fd\u0161i\u0165 citlivos\u0165 na inzul\u00edn, v\u00e1m m\u00f4\u017ee pom\u00f4c\u0165 zlep\u0161i\u0165 aj va\u0161e zdravie. Ned\u00e1vny v\u00fdskum v\u0161ak uk\u00e1zal pr\u00e1\u0161kov\u00fa formu inositolu<\/a> ako \u010fal\u0161\u00ed doplnok, ktor\u00fd m\u00f4\u017ee zn\u00ed\u017ei\u0165 inzul\u00ednov\u00fa rezistenciu. Ak ste sa na z\u00e1klade n\u00e1\u0161ho \u010dl\u00e1nku rozhodli podnikn\u00fa\u0165 nejak\u00e9 zlep\u0161enia, dajte n\u00e1m vedie\u0165 v koment\u00e1roch ni\u017e\u0161ie, ktor\u00fd tip sa v\u00e1m (alebo niekomu z va\u0161ich zn\u00e1mych) osved\u010dil.<\/p>\n\n\n\n\n

\n\n
\n\n
\u201cZdroje\u201d<\/summary>\n\n

(1) Gower, Barbara A, and Amy M Goss. \u201cA lower-carbohydrate, higher-fat diet reduces abdominal and intermuscular fat and increases insulin sensitivity in adults at risk of type 2 diabetes.\u201d The Journal of nutrition vol. 145,1 (2015): 177S-83S. doi:10.3945\/jn.114.195065<\/p>\n\n\n\n

(2) Aeberli, Isabelle et al. \u201cModerate amounts of fructose consumption impair insulin sensitivity in healthy young men: a randomized controlled trial.\u201d Diabetes care vol. 36,1 (2013): 150-6. doi:10.2337\/dc12-0540<\/p>\n\n\n\n

(3) Jornayvaz, Fran\u00e7ois R et al. \u201cA high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain.\u201d American journal of physiology. Endocrinology and metabolism vol. 299,5 (2010): E808-15. doi:10.1152\/ajpendo.00361.2010<\/p>\n\n\n\n

(4) Holm\u00e4ng, A, and P Bj\u00f6rntorp. \u201cThe effects of cortisol on insulin sensitivity in muscle.\u201d Acta physiologica Scandinavica vol. 144,4 (1992): 425-31. doi:10.1111\/j.1748-1716.1992.tb09316.x<\/p>\n\n\n\n

(5) Skoluda, Nadine et al. \u201cElevated hair cortisol concentrations in endurance athletes.\u201d Psychoneuroendocrinology vol. 37,5 (2012): 611-7. doi:10.1016\/j.psyneuen.2011.09.001<\/p>\n\n\n\n

(6) Kanaley, Jill et al. \u201cCortisol and Growth Hormone Responses to Exercise at Different Times of Day.\u201d The Journal of Clinical Endocrinology & Metabolism, Volume 86, Issue 6, 1 June 2001, Pages 2881\u20132889, https:\/\/doi.org\/10.1210\/jcem.86.6.7566<\/p>\n\n\n\n

(7) Bj\u00f8rndal, Bodil et al. \u201cPhospholipids from herring roe improve plasma lipids and glucose tolerance in healthy, young adults.\u201d Lipids in health and disease vol. 13 82. 17 May. 2014, doi:10.1186\/1476-511X-13-82<\/p>\n\n\n\n

(8) Capel, Fr\u00e9d\u00e9ric et al. \u201cDHA at nutritional doses restores insulin sensitivity in skeletal muscle by preventing lipotoxicity and inflammation.\u201d The Journal of nutritional biochemistry vol. 26,9 (2015): 949-59. doi:10.1016\/j.jnutbio.2015.04.003<\/p>\n\n\n\n

(9) Cassia cinnamon for the attenuation of glucose intolerance and insulin resistance resulting from sleep loss (J Med Food. 2009 Jun;12(3):467-72)<\/p>\n\n\n\n

(10) Mahluji, Sepide et al. \u201cEffects of ginger (Zingiber officinale) on plasma glucose level, HbA1c and insulin sensitivity in type 2 diabetic patients.\u201d International journal of food sciences and nutrition vol. 64,6 (2013): 682-6. doi:10.3109\/09637486.2013.775223<\/p>\n\n\n\n

(11) Ghorbani, Zeinab et al. \u201cAnti-hyperglycemic and insulin sensitizer effects of turmeric and its principle constituent curcumin.\u201d International journal of endocrinology and metabolism vol. 12,4 e18081. 1 Oct. 2014, doi:10.5812\/ijem.18081<\/p>\n\n\n\n

(12) Talaei, A., Mohamadi, M. & Adgi, Z. The effect of vitamin D on insulin resistance in patients with type 2 diabetes. Diabetol Metab Syndr 5, 8 (2013). https:\/\/doi.org\/10.1186\/1758-5996-5-8<\/p>\n\n\n\n

(13) Zhang, Hai et al. \u201cTreatment of obesity and diabetes using oxytocin or analogs in patients and mouse models.\u201d PloS one vol. 8,5 e61477. 20 May. 2013, doi:10.1371\/journal.pone.0061477<\/p>\n\n\n\n

(14) Dong, Hui et al. \u201cBerberine in the treatment of type 2 diabetes mellitus: a systemic review and meta-analysis.\u201d Evidence-based complementary and alternative medicine : eCAM vol. 2012 (2012): 591654. doi:10.1155\/2012\/591654<\/p>\n\n\n\n

(15) Berberine for diabetes mellitus type 2. Steriti R. Natural Medicine Journal 2010 October;2(10):5-6<\/p>\n\n\n\n

(16) Chen, Chunhua et al. \u201cBerberine inhibits PTP1B activity and mimics insulin action.\u201d Biochemical and biophysical research communications vol. 397,3 (2010): 543-7. doi:10.1016\/j.bbrc.2010.05.153<\/p>\n\n\n\n

(17) Turner, Nigel et al. \u201cBerberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action.\u201d Diabetes vol. 57,5 (2008): 1414-8. doi:10.2337\/db07-1552<\/p>\n\n\n\n

(18) Lee, Yun S et al. \u201cBerberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states.\u201d Diabetes vol. 55,8 (2006): 2256-64. doi:10.2337\/db06-0006<\/p>\n\n\n\n

(19) Ma, Xiao et al. \u201cBerberine-induced activation of 5\u2032-adenosine monophosphate-activated protein kinase and glucose transport in rat skeletal muscles.\u201d Metabolism: clinical and experimental vol. 59,11 (2010): 1619-27. doi:10.1016\/j.metabol.2010.03.009<\/p>\n\n\n\n

(20) Hwang, Jin-Taek et al. \u201cAMP-activated protein kinase: a potential target for the diseases prevention by natural occurring polyphenols.\u201d New biotechnology vol. 26,1-2 (2009): 17-22. doi:10.1016\/j.nbt.2009.03.005<\/p>\n\n\n\n<\/details>\n\n<\/div>\n \n<\/div>\n\n\n\n\n\n\n

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