{"id":238087,"date":"2020-09-07T09:00:00","date_gmt":"2020-09-07T08:00:00","guid":{"rendered":"https:\/\/eu.intelligentlabs.org\/inozitol-a-pcos-doplnok-ktory-skutocne-funguje\/"},"modified":"2025-09-18T14:31:59","modified_gmt":"2025-09-18T13:31:59","slug":"inozitol-a-pcos-doplnok-ktory-skutocne-funguje","status":"publish","type":"post","link":"https:\/\/eu.intelligentlabs.org\/sk-sk\/inozitol-a-pcos-doplnok-ktory-skutocne-funguje\/","title":{"rendered":"Inozitol a PCOS \u2013 v\u00fd\u017eivov\u00fd doplnok, ktor\u00fd skuto\u010dne funguje!"},"content":{"rendered":"\n

Syndr\u00f3m polycystick\u00fdch vaje\u010dn\u00edkov (PCOS) postihuje \u017eeny zo v\u0161etk\u00fdch spolo\u010densk\u00fdch vrstiev. Nemus\u00ed to by\u0165 \u017eivot ohrozuj\u00face ochorenie, ale ak sa nebudete lie\u010di\u0165, m\u00f4\u017ee vies\u0165 aj k v\u00e1\u017enej\u0161\u00edm zdravotn\u00fdm stavom, ako je cukrovka II.typu a kardiovaskul\u00e1rne probl\u00e9my. V tomto \u010dl\u00e1nku sa dozviete, \u010di je u\u017e\u00edvanie inozitolu \u00fa\u010dinn\u00e1 mo\u017enos\u0165 lie\u010dby pri diagn\u00f3ze PCOS. Inozitol a PCOS spolu s\u00favisia. Ak budete \u010d\u00edta\u0165 a\u017e do konca, prezrad\u00edme v\u00e1m, ktor\u00fd je najlep\u0161\u00ed doplnok s inozitolom na trhu.<\/p>\n\n\n\n

\u010co presne je inozitol?<\/strong><\/h2>\n\n\n\n

Inozitol je prirodzene sa vyskytuj\u00faca forma cukru, ktor\u00e1 sa be\u017ene nach\u00e1dza v zrn\u00e1ch, ovoc\u00ed a orechoch. Pomaran\u010de a mel\u00f3ny s\u00fa dva perfektn\u00e9 pr\u00edklady ovocia s vysok\u00fdm obsahom inozitolu. Na\u0161e telo tie\u017e vyr\u00e1ba inozitol z gluk\u00f3zy, tak\u017ee n\u00e1m tento element nie je v\u00f4bec cudz\u00ed. Na\u0161e obli\u010dky v skuto\u010dnosti tvoria asi dva gramy inozitolu<\/a> denne.<\/p>\n\n\n\n

Inozitol je hlavnou s\u00fa\u010das\u0165ou na\u0161ich bunkov\u00fdch membr\u00e1n. Ovplyv\u0148uje neurotransmitery v mozgu vr\u00e1tane horm\u00f3nov, zodpovedn\u00fdch za na\u0161u celkov\u00fa n\u00e1ladu – seroton\u00ednu a dopam\u00ednu. A v\u010faka svojmu \u00fa\u010dinku na inzul\u00edn pom\u00e1ha pri kontrole cukru v krvi.<\/p>\n\n\n\n

Pozn\u00e1me 9 izom\u00e9rnych foriem inozitolu, pri\u010dom najbe\u017enej\u0161ou formou je myo-inozitol<\/strong>. Ak to telo vy\u017eaduje, m\u00f4\u017ee sa zmeni\u0165 na in\u00e9 formy, ako je napr\u00edklad d-chiro-inozito<\/strong>l (1). V na\u0161om \u010dl\u00e1nku sa dozviete viac o tom, ako myo-inozitol a d-chiro-inozitol spolupracuj\u00fa v boji proti PCOS, tak\u017ee ur\u010dite \u010d\u00edtajte \u010falej!<\/p>\n\n\n\n

Mo\u017eno ste to nevedeli, ale pr\u00e1\u0161kov\u00fd inozitol chut\u00ed sladko asi o polovicu menej ako klasick\u00fd cukor a vo filmoch<\/a> sa be\u017ene pou\u017e\u00edva ako n\u00e1hrada koka\u00ednu. Ke\u010f teda nabud\u00face uvid\u00edte svojho ob\u013e\u00faben\u00e9ho herca \u0161\u0148upa\u0165 biely pr\u00e1\u0161ok, bude to pravdepodobne n\u00e1\u0161 zn\u00e1my inozitol!<\/p>\n\n\n\n

PCOS a rezistencia na inzul\u00edn<\/strong><\/h2>\n\n\n\n
\"\u017eena<\/figure>\n\n\n\n

Lie\u010dba PCOS tradi\u010dne v na\u0161ej spolo\u010dnosti zah\u0155\u0148ala lie\u010dbu jednotliv\u00fdch sympt\u00f3mov, to znamen\u00e1, \u017ee samostatne sa lie\u010dila nepr\u00edtomn\u00e1 men\u0161tru\u00e1cia, vypad\u00e1vanie vlasov alebo extr\u00e9mny pr\u00edrastok na hmotnosti at\u010f. Hlavn\u00e1 pr\u00ed\u010dina sa v\u0161ak \u010dasto nelie\u010dila, tak\u017ee sa tento stav pacientk\u00e1m neust\u00e1le vracia. <\/p>\n\n\n\n

Hlavn\u00e1 pr\u00ed\u010dina PCOS je st\u00e1le bohu\u017eia\u013e nezn\u00e1ma, ale existuje nieko\u013eko mo\u017en\u00fdch te\u00f3ri\u00ed. Jedn\u00fdm z nich je dedi\u010dn\u00fd stav, ktor\u00fd sa e\u0161te zhor\u0161uje pr\u00edtomnos\u0165ou obezity (2). \u010eal\u0161\u00edm je pr\u00edpad, ke\u010f s\u00fa doj\u010dat\u00e1 \u017eensk\u00e9ho pohlavia vystaven\u00e9 vysokej hladine androg\u00e9nov in utero<\/em>, \u010do ich rob\u00ed nesk\u00f4r n\u00e1chylnej\u0161ie na PCOS (3). A nakoniec inzul\u00ednov\u00e1 rezistencia alebo necitlivos\u0165 na inzul\u00edn (4). V tomto \u010dl\u00e1nku sa zameriame na lie\u010dbu inzul\u00ednovej rezistencie a boj so sympt\u00f3mami PCOS. Inozitol a PCOS spolu s\u00favisia viac, ne\u017e si mysl\u00edme.<\/p>\n\n\n\n

\u010co m\u00e1 inzul\u00edn do \u010dinenia s PCOS?<\/strong><\/h3>\n\n\n\n

Inzul\u00edn je horm\u00f3n, ktor\u00fd premie\u0148a sacharidy z potrav\u00edn, ktor\u00e9 konzumujete, na cukor alebo gluk\u00f3zu, tak\u017ee ho telo m\u00f4\u017ee vyu\u017e\u00edva\u0165 na tvorbu energiu. Reguluje hladinu cukru v krvi ukladan\u00edm nadbyto\u010dnej gluk\u00f3zy do pe\u010dene, svalov a tukov\u00fdch buniek. Telo pou\u017eije t\u00fato ulo\u017een\u00fa gluk\u00f3zu, ke\u010f hladina cukru v krvi klesne. Tento stav zvy\u010dajne nast\u00e1va, ak ste hladn\u00e9 alebo ste pr\u00e1ve skon\u010dili nejak\u00fa nam\u00e1hav\u00fa fyzick\u00fa aktivitu, ktor\u00e1 v\u00e1m spotrebovala ve\u013ea energie (5). <\/p>\n\n\n\n

Ke\u010f v\u0161ak zjete pr\u00edli\u0161 ve\u013ea sacharidov bez toho, aby ste vydali rovnak\u00e9 mno\u017estvo energie (napr. kv\u00f4li sedav\u00e9mu \u017eivotn\u00e9mu \u0161t\u00fdlu), hladina cukru v krvi m\u00f4\u017ee zosta\u0165 nebezpe\u010dne vysok\u00e1. V\u00e1\u0161 pankreas za\u010dne vyr\u00e1ba\u0165 viac inzul\u00ednu, aby sa pok\u00fasil zn\u00ed\u017ei\u0165 hladinu cukru v krvi.<\/p>\n\n\n\n

Zv\u00fd\u0161en\u00e9 hladiny inzul\u00ednu po dlh\u0161iu dobu v\u0161ak ved\u00fa k inzul\u00ednovej rezistencii, to znamen\u00e1, \u017ee inzul\u00edn u\u017e nefunguje tak, ako by mal. Hladina cukru v krvi teda nie je kontrolovan\u00e1. Tento stav m\u00f4\u017ee prer\u00e1s\u0165 do v\u00e1\u017enych zdravotn\u00fdch komplik\u00e1ci\u00ed, ako je cukrovka II. typu, slepota, zlyh\u00e1vanie obli\u010diek a srdcov\u00e9 choroby.<\/p>\n\n\n\n

Kv\u00f4li inzul\u00ednovej rezistencii sa va\u0161e horm\u00f3ny za\u010dn\u00fa takisto spr\u00e1va\u0165 inak. Hladina estrog\u00e9nu kles\u00e1 a hladina testoster\u00f3nu (mu\u017esk\u00e9ho horm\u00f3nu) st\u00fapa. To je d\u00f4vod, pre\u010do sa mnoh\u00e9 pr\u00edznaky PCOS prejavuj\u00fa vo forme zmien, typick\u00fdch pre mu\u017eov. Ide napr\u00edklad o ne\u017eiaduci rast ochlpenia na tv\u00e1ri (f\u00fazy, brada), nepravidelnos\u0165 alebo stratu men\u0161tru\u00e1cie a rednutie vlasov na vrchu hlavy, rovnako ako prebieha ple\u0161atenie mu\u017eov (6).<\/p>\n\n\n\n

\"Inozitol<\/figure>\n\n\n\n

Vytrval\u00fd bojovn\u00edk Inozitol a PCOS <\/strong><\/h2>\n\n\n\n

Ni\u010d nie je straten\u00e9, existuje v\u0161ak nieko\u013eko sp\u00f4sobov, ako m\u00f4\u017ee inozitol pom\u00f4c\u0165 \u017een\u00e1m postihnut\u00fdm PCOS:<\/p>\n\n\n\n

Zni\u017euje rezistenciu na inzul\u00edn<\/strong><\/p>\n\n\n\n

Costantino a jeho vedeck\u00fd t\u00edm uskuto\u010dnili dvojit\u00fa slep\u00fa \u0161t\u00fadiu na 42 \u017een\u00e1ch s diagn\u00f3zou PCOS v kombin\u00e1cii inozitol a PCOS. Polovicu \u017eien lie\u010dili myo-inozitolom a pridanou kyselinou listovou. Druhej polovici bola podan\u00e1 iba samotn\u00e1 kyselina listov\u00e1. Rozdiel medzi t\u00fdmito dvoma skupinami bol ohromuj\u00faci. Prv\u00e1 skupina preuk\u00e1zala v\u00fdrazn\u00e9 zv\u00fd\u0161enie citlivosti na inzul\u00edn, ni\u017e\u0161\u00ed krvn\u00fd tlak, ni\u017e\u0161iu hladinu triglyceridov a ni\u017e\u0161ie hladiny testoster\u00f3nu v porovnan\u00ed s druhou skupinou \u017eien (7).<\/p>\n\n\n\n

Zlep\u0161uje \u010dinnos\u0165 vaje\u010dn\u00edkov<\/strong><\/p>\n\n\n\n

Ovul\u00e1cia je prv\u00fdm d\u00f4le\u017eit\u00fdm krokom k plodnosti a tehotenstvu. U \u017eien s nepravidelnou men\u0161tru\u00e1ciou ide o prv\u00fd pr\u00edznak, ktor\u00fd je potrebn\u00e9 vylie\u010di\u0165 \u010do najsk\u00f4r. V \u0161t\u00fadii zah\u0155\u0148aj\u00facej 50 \u017eien s PCOS a inzul\u00ednovou rezistenciou im vedci pod\u00e1vali myo-inozitol. Zistili, \u017ee tento krok pomohol zlep\u0161i\u0165 ich citlivos\u0165 na inzul\u00edn a tie\u017e index telesnej hmotnosti – BMI. Op\u00e4tovn\u00e1 ovul\u00e1cia sa objavila u 29 \u017eien (nesk\u00f4r 11 \u017eien z  t\u00fdchto 29 \u00faspe\u0161ne otehotnelo) (8).<\/p>\n\n\n\n

Zvy\u0161uje kvalitu vaj\u00ed\u010dok<\/strong><\/p>\n\n\n\n

Kvalita vaj\u00ed\u010dok m\u00f4\u017ee predznamena\u0165 rozdiel medzi  \u0161tandardne prebiehaj\u00facim a problematick\u00fdm tehotenstvom. \u017deny s PCOS nielen\u017ee trpia nepravidelnou men\u0161tru\u00e1ciou a neplodnos\u0165ou, ale probl\u00e9mom je aj zl\u00e1 kvalita ich vaj\u00ed\u010dok. Na\u0161\u0165astie u\u017e\u00edvanie doplnkov s myo-inozitolom zlep\u0161uje kvalitu vaj\u00ed\u010dok u pacientiek s PCOS, \u010do vedie k neskor\u0161iemu zdrav\u00e9mu tehotenstvu (9). Inozitol a PCOS teda spolu s\u00favisia. <\/p>\n\n\n\n

Chr\u00e1ni pred tehotenskou cukrovkou<\/strong><\/p>\n\n\n\n

Tehotn\u00e9 \u017eeny, ktor\u00e9 trpia inzul\u00ednovou rezistenciou, s\u00fa vystaven\u00e9 vysok\u00e9mu riziku vzniku gesta\u010dn\u00e9ho diabetes mellitus (GDM) – tzv. tehotenskej cukrovky. Vedci v\u0161ak zistili, \u017ee u\u017e\u00edvan\u00edm doplnkov s myo-inozitolom sa pravdepodobnos\u0165 v\u00fdskytu GDM u \u017eien v\u00fdznamne zn\u00ed\u017eila. \u017deny tie\u017e porodili men\u0161ie a zdrav\u0161ie deti v neskor\u0161om gesta\u010dnom obdob\u00ed (10).<\/p>\n\n\n\n

Zlep\u0161uje krvn\u00fd tlak a hladinu trygliceridov v krvi <\/strong><\/p>\n\n\n\n

Myo-inozitol m\u00f4\u017ee by\u0165 hlavn\u00fdm inozitolom v tele, ale \u0161t\u00fadia uskuto\u010dnen\u00e1 na d-chiro-inozitole uk\u00e1zala, \u017ee okrem zlep\u0161enia citlivosti na inzul\u00edn u pacientiek s PCOS, zn\u00ed\u017eil dokonca aj plazmatick\u00e9 koncentr\u00e1cie triglyceridov u \u017eien. Okrem toho sa v\u00fdznamne zn\u00ed\u017eil aj diastolick\u00fd a systolick\u00fd krvn\u00fd tlak pacientiek (11). Inozitol teda vpl\u00fdva aj na sympt\u00f3my PCOS. <\/p>\n\n\n\n

Zni\u017euje hladinu testoster\u00f3nu<\/strong><\/p>\n\n\n\n

Vysok\u00e1 hladina testoster\u00f3nu je zodpovedn\u00e1 u \u017eien s PCOS za v\u00fdskyt nepr\u00edjemn\u00e9ho akn\u00e9, rednutie vlasov a hirzutizmus. Ak trp\u00edte t\u00fdmito pr\u00edznakmi, zv\u00e1\u017ete u\u017e\u00edvanie inozitolu, ktor\u00fd sa preuk\u00e1zal ako \u00fa\u010dinn\u00fd pr\u00e1ve pri PCOS. V testovacej \u0161t\u00fadii mali vedci mo\u017enos\u0165 sledova\u0165 v\u00fdrazn\u00e9 zn\u00ed\u017eenie hlad\u00edn testoster\u00f3nu lie\u010den\u00edm \u017eien kombin\u00e1ciou myo-inozitolu a kyseliny listovej (7).<\/p>\n\n\n\n

\"\u017eena<\/figure>\n\n\n\n

U\u017e\u00edvanie doplnkov s inozitolom pri PCOS \u2013 ak\u00e9 je to najlep\u0161ie rie\u0161enie?<\/strong><\/h2>\n\n\n\n

U\u017e\u00edvanie ve\u013ek\u00e9ho mno\u017estva potrav\u00edn bohat\u00fdch na inozitol ka\u017ed\u00fd de\u0148 m\u00f4\u017ee s\u00edce pom\u00f4c\u0165 pri diagn\u00f3ze PCOS, mus\u00edte v\u0161ak by\u0165 v tomto oh\u013eade extr\u00e9mne disciplinovan\u00e9. To znamen\u00e1, \u017ee nem\u00f4\u017eete podv\u00e1dza\u0165 a potajomky si vychutn\u00e1va\u0165 nezdrav\u00e9 potraviny bohat\u00e9 na cukor. Preto je dop\u013a\u0148anie inozitolu nevyhnutnos\u0165ou. Pr\u00edjem inozitolu z potravy \u010dasto nesta\u010d\u00ed na zlep\u0161enie a zv\u00fd\u0161enie citlivosti na inzul\u00edn<\/a>.<\/p>\n\n\n\n

<\/p>\n\n\n\n

Na z\u00e1ver<\/strong><\/h2>\n\n\n\n

Na lie\u010dbu PCOS mo\u017eno e\u0161te neexistuje liek, ale pr\u00edznaky tohto ochorenia s\u00fa zvl\u00e1dnute\u013en\u00e9. Zdrav\u00fd \u017eivotn\u00fd \u0161t\u00fdl – konzum\u00e1cia stravy vhodnej pre PCOS a vy\u0161\u0161ia fyzick\u00e1 aktivita – m\u00f4\u017eu pom\u00f4c\u0165 zlep\u0161i\u0165 va\u0161e probl\u00e9my. Pom\u00e1ha aj v\u00fd\u017eivov\u00fd doplnok s inozitolom. Aby ste sa uistili, \u017ee sa va\u0161e pr\u00edznaky u\u017e nikdy nevr\u00e1tia, je d\u00f4le\u017eit\u00e9 tento nov\u00fd zdrav\u00fd \u017eivotn\u00fd \u0161t\u00fdl aj d\u00f4kladne dodr\u017eiava\u0165. Ak ste vysk\u00fa\u0161ali Chromositol-F (alebo ak\u00fdko\u013evek in\u00fd doplnok s inozitolom) pri lie\u010dbe va\u0161ich pr\u00edznakov PCOS, dajte n\u00e1m vedie\u0165 v koment\u00e1roch pod \u010dl\u00e1nkom!<\/p>\n\n\n\n

Zdroje:<\/strong><\/p>\n\n\n\n

(1) Larner, Joseph et al. \u201cD-chiro-inositol glycans in insulin signaling and insulin resistance.\u201d Molecular medicine (Cambridge, Mass.) vol. 16,11-12 (2010): 543-52. doi:10.2119\/molmed.2010.00107<\/p>\n\n\n\n

(2) Legro RS, Strauss JF (2002). \u201cMolecular progress in infertility: polycystic ovary syndrome\u201d. Fertil. Steril. 78 (3): 569\u201376. doi:10.1016\/S0015-0282(02)03275-2<\/p>\n\n\n\n

(3) Panagiota Filippou, Roy Homburg, Is foetal hyperexposure to androgens a cause of PCOS?, Human Reproduction Update, Volume 23, Issue 4, July-August 2017, Pages 421\u2013432, https:\/\/doi.org\/10.1093\/humupd\/dmx013<\/p>\n\n\n\n

(4) Lisa J. Moran, Marie L. Misso, Robert A. Wild, Robert J. Norman, Impaired glucose tolerance, type 2 diabetes and metabolic syndrome in polycystic ovary syndrome: a systematic review and meta-analysis, Human Reproduction Update, Volume 16, Issue 4, July-August 2010, Pages 347\u2013363, https:\/\/doi.org\/10.1093\/humupd\/dmq001<\/p>\n\n\n\n

(5) Wilcox, Gisela. \u201cInsulin and insulin resistance.\u201d The Clinical biochemist. Reviews vol. 26,2 (2005): 19-39.<\/p>\n\n\n\n

(6) Rodriguez Paris, Valentina, and Michael J Bertoldo. \u201cThe Mechanism of Androgen Actions in PCOS Etiology.\u201d Medical sciences (Basel, Switzerland) vol. 7,9 89. 28 Aug. 2019, doi:10.3390\/medsci7090089<\/p>\n\n\n\n

(7) Costantino, D et al. \u201cMetabolic and hormonal effects of myo-inositol in women with polycystic ovary syndrome: a double-blind trial.\u201d European review for medical and pharmacological sciences vol. 13,2 (2009): 105-10.<\/p>\n\n\n\n

(8) Kamenov, Zdravko et al. \u201cOvulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance.\u201d Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology vol. 31,2 (2015): 131-5. doi:10.3109\/09513590.2014.964640<\/p>\n\n\n\n

(9) Zheng, Xiangqin et al. \u201cInositol supplement improves clinical pregnancy rate in infertile women undergoing ovulation induction for ICSI or IVF-ET.\u201d Medicine vol. 96,49 (2017): e8842. doi:10.1097\/MD.0000000000008842<\/p>\n\n\n\n

(10) Matarrelli, Barbara et al. \u201cEffect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial.\u201d The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians vol. 26,10 (2013): 967-72. doi:10.3109\/14767058.2013.766691<\/p>\n\n\n\n

(11) Nestler, J E et al. \u201cOvulatory and metabolic effects of D-chiro-inositol in the polycystic ovary syndrome.\u201d The New England journal of medicine vol. 340,17 (1999): 1314-20. doi:10.1056\/NEJM199904293401703<\/p>\n","protected":false},"excerpt":{"rendered":"

Syndr\u00f3m polycystick\u00fdch vaje\u010dn\u00edkov (PCOS) postihuje \u017eeny zo v\u0161etk\u00fdch spolo\u010densk\u00fdch vrstiev. Nemus\u00ed to by\u0165 \u017eivot ohrozuj\u00face ochorenie, ale ak sa nebudete lie\u010di\u0165, m\u00f4\u017ee vies\u0165 aj k v\u00e1\u017enej\u0161\u00edm zdravotn\u00fdm stavom, ako je cukrovka II.typu a kardiovaskul\u00e1rne probl\u00e9my. V tomto \u010dl\u00e1nku sa dozviete, \u010di je u\u017e\u00edvanie inozitolu \u00fa\u010dinn\u00e1 mo\u017enos\u0165 lie\u010dby pri diagn\u00f3ze PCOS. Inozitol a PCOS spolu 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