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<\/figure>\n<\/div>\n\n\nMyo-inositol is the most common and abundant form of inositol<\/strong>, all the others occur in minimal quantities. This is why, by default, inositol refers to myo inositol<\/strong>.<\/p>\n\n\n\n Moving forward, every time I mention inositol in this article, know that I\u2019m actually referring to myo inositol.<\/p>\n<\/blockquote>\n\n\n\n Inositol is a form of sugar alcohol that occurs naturally in fruits, nuts, and grains. Our bodies also produce inositol from glucose and make use of it in various biochemical processes. It\u2019s found in high quantities in our brain and other tissues. Additionally, our kidneys also produce about 2 grams of inositol daily.<\/p>\n\n\n\n If you\u2019re on the fence about taking inositol or wondering why it\u2019s such a big deal to a lot of women, then scroll down to know more about it!<\/p>\n\n\n\n When taken together with d-chiro-inositol (one of the aforementioned 9 inositol isomers), myo inositol can help manage PCOS symptoms. This includes excessive acne, weight gain, hirsutism, female pattern baldness, irregular periods, and more (I\u2019ll expound more on how inositol manages these symptoms later on).<\/p>\n\n\n\n But don\u2019t just take any inositol supplement \u2013 look for one that has at least the scientifically recommended 40:1 myo-inositol to d-chiro-inositol ratio<\/strong> (1<\/a>).<\/p>\n\n\n\n Insulin controls blood sugar levels in the body. But when your body starts failing to respond to insulin, it can cause insulin resistance. This, in turn, can lead to diabetes, cardiovascular disease, metabolic syndrome, and more.<\/p>\n\n\n\n According to a 2018 study published in the International Journal of Endocrinology, inositol can help normalize blood sugar levels and prevent hyperinsulinemia <\/strong>(too much insulin in the blood) from occurring. As such, inositol has become a viable treatment option for improving insulin sensitivity, especially among PCOS patients (2<\/a>).<\/p>\n\n\n\n It\u2019s a sad fact that PCOS patients find it difficult to conceive. While there are a number of reasons that contribute to reproductive problems, one of them is the quality of a woman\u2019s egg. You see, a higher quality egg has a better chance of developing into an embryo<\/strong>, implanting in the uterus<\/strong>, and finally, culminating in the birth of a healthy baby<\/strong>.<\/p>\n\n\n\n If you\u2019re trying to get pregnant, you\u2019ll be happy to know that supplementing with myo-inositol can help improve egg quality in PCOS patients (3<\/a>). But that\u2019s not all. Inositol plus folic acid (vs folic acid alone) m<\/strong>ay improve oocyte quality in PCOS women<\/strong> (4<\/a>).<\/p>\n\n\n\n If your partner has male reproductive issues, let them take an inositol supplement! According to a 2016 study done on 45 males with metabolic syndrome, inositol (along with other nutrients like folic acid, vitamin E, and selenium) helped the men improve insulin sensitivity and raised their testosterone levels as well. Perhaps more importantly, sperm concentration and motility may also<\/strong> be i<\/b><\/span>mproved<\/strong> (5<\/a>).<\/p>\n\n\n\n By now you know that inositol can improve insulin sensitivity which leads to even more positive changes in your body. This includes a noticeable reduction in weight (this is because insulin resistance can lead to weight gain), restored regular menses, and of course, improved egg quality. All these factors help support fertility in PCOS patients!<\/p>\n\n\n\n The male hormone isn\u2019t just for men. It\u2019s also present in women, but those with PCOS have higher testosterone levels than normal. This can lead to masculine features in PCOS women, such as female pattern baldness, excessive hair growth in non-feminine body parts, acne, and the loss of regular menses.<\/p>\n\n\n\n The symptoms can really affect a woman\u2019s self-esteem. Fortunately, inositol has shown a lot of promise in this regard. In a clinical trial, researchers found that treating patients with the power combo of<\/strong> inositol and folic acid led to significantly lower testosterone levels <\/strong>(8<\/a>)!<\/p>\n\n\n\n Bearded women do exist. While some have learned to embrace and live with their condition, many others aren\u2019t happy with it at all. <\/p>\n\n\n\n In a 2008 study, 46 hirsute women were given myo-inositol for 6 months. As you can probably guess, androgen (male hormone) levels decreased and estrogen (female hormone) concentrations increased. This helped the women finally get rid of the unwanted hair growth<\/strong> (10<\/a>).<\/p>\n\n\n\n High triglyceride levels can lead to stroke and heart disease. Most people don\u2019t display symptoms until it reaches extremely high levels. By then, it would already be too late for many.<\/p>\n\n\n\n By taking inositol, you can reduce your triglycerides level and reduce the risk of cardiovascular disease (9<\/a>).<\/p>\n\n\n\n Tabrizi et al.\u2019s study (9) has also shown that inositol can lead to reduced LDL cholesterol and total cholesterol levels. LDL stands for low-density lipoprotein or the \u201cbad\u201d cholesterol. Too much LDL can lead to a buildup of plaque in the arteries, which as you can probably imagine, means bad news for you. A blocked artery can rapidly lead to a heart attack or stroke.<\/p>\n\n\n\n While inositol has no effect on HDL (high-density lipoprotein) or the \u201cgood\u201d cholesterol, it nevertheless made an impact on total cholesterol levels. So, overall, inositol bodes well for your cholesterol and your heart health<\/strong> in general!<\/p>\n\n\n\n High testosterone levels in PCOS patients can cause excessive production of sebum. It can clog up your pores and cause acne breakouts all over your body. But with inositol\u2019s testosterone-normalizing power (see point #9), you also get the added benefit of acne-free skin!<\/p>\n\n\n\n Women who took 4g of inositol for 6 months showed skin improvements and exhibited lower DHEAS blood levels (DHEAS is a hormone that makes testosterone) (11<\/a>). <\/p>\n\n\n\n According to the World Health Organization<\/a>, more than 264 million people suffer from depression worldwide.<\/p>\n\n\n\n Treating depression usually involves therapy and medication. But inositol may also help. A study observed 28 patients who were given 12g of inositol daily for 4 weeks. By the end of the study, the patients showed significant mental changes<\/strong>. Additionally, no changes were observed in blood, kidney and liver function, which is a good sign (12<\/a>).<\/p>\n\n\n\n Panic disorder is a severe form of anxiety. If you or anyone you know suffers from this crippling condition, try taking inositol. A double-blind study showed that patients who took 18g of inositol for 1 month had fewer panic attacks per week than those taking fluvoxamine<\/strong> (an antidepressant). The inositol group also experienced fewer episodes of nausea and tiredness, two common side effects of fluvoxamine (13<\/a>).<\/p>\n\n\n\n Similar results were reported by another study where patients were given 12g of inositol per day. They too experienced fewer panic attack episodes with minimal side effects (12).<\/p>\n\n\n\n A handful of inositol studies show promising results for bipolar disorder (BPD). A clinical trial done on children 5-12 years of age diagnosed with BPD were given either (a) inositol, (b) omega 3, or (c) inositol + omega 3. The group given inositol + omega 3 showed significant improvements in their BPD symptoms<\/strong> (14<\/a>).<\/p>\n\n\n\n On a morbid note, a postmortem study found that people who had BPD and those who committed suicide had one thing in common \u2013 they exhibited significantly fewer amounts of inositol in their frontal cortex (15<\/a>). This part of the brain is responsible for important cognitive skills such as impulse control, judgment, problem solving, memory, and language.<\/p>\n\n\n\n Lithium is an antimanic drug that can help prevent manic episodes in people suffering from bipolar disorder. However, one of its notable side effects is psoriasis.<\/p>\n\n\n\n In a case report published in the Cases Journal, a patient receiving lithium for BPD treatment experienced severe psoriasis. Lithium was discontinued and replaced with 3g of inositol per day. 4 years later, the patient is still on inositol – both her BPD and psoriasis are well under control (16<\/a>).<\/p>\n\n\n\n Pregnancy is hard enough as it is. But when a woman is diagnosed with gestational diabetes mellitus (GDM), it can complicate the pregnancy even more. It puts both mother and baby in danger. Due to its positive effects on insulin sensitivity, inositol is also recognized as a treatment option for GDM<\/strong>.<\/p>\n\n\n\n A 2019 study published in the Cureus journal confirms that inositol is a safe supplement. Inositol can reduce the risk of GDM amongst overweight and obese pregnant women. Moreover, women with a family history of type 2 diabetes and\/or PCOS can also take inositol to reduce the risk of GDM (17<\/a>).<\/p>\n\n\n\n And here\u2019s more good news – women who took myo-inositol during pregnancy also delivered smaller babies at a later gestational age<\/strong> (18<\/a>).<\/p>\n\n\n\n Preterm infants are often born with underdeveloped lungs and experience breathing issues from the moment they are born. Unfortunately, there’s not a lot of inositol studies done on preterm infants.<\/p>\n\n\n\n But one early study showed promising results. The preterm infants given inositol required less mechanical ventilation and resulted in fewer deaths <\/strong>(compared to the babies who didn\u2019t receive inositol) (19<\/a>).<\/p>\n\n\n\n However, a more recent review recommends not using inositol on preterm infants. Apparently, the researchers did not see any significant reduction in inositol supplementation vs infant death, infections, brain bleeds, eye problems, lung problems and gastrointestinal problems (20<\/a>).<\/p>\n\n\n\n Studies suggest that women are at risk of developing metabolic syndrome once they transition over to the postmenopausal stage of life. One study shows that 13.7% of newly-menopause women<\/strong> who did not have diabetes or metabolic syndrome prior to menopause suddenly developed metabolic syndrome<\/strong>. This makes women at risk of developing cardiovascular disease during menopause (21<\/a>).<\/p>\n\n\n\n Don\u2019t fret if you belong to this demographic because inositol has shown a lot of promise at treating metabolic syndrome in postmenopausal ladies! A study published in the Menopause journal showed that taking 2g of myo inositol plus eating a healthy diet<\/a><\/strong> resulted in improved health. Blood pressure, HOMA index, cholesterol, and triglyceride levels all showed significant improvement in the volunteers (22<\/a>).<\/p>\n\n\n\n Inositol may not be marketed as a weight loss product, but weight loss is one positive sign of improved insulin sensitivity (23<\/a>). As we\u2019ve learned in point #2, inositol helps promote insulin sensitivity by normalizing blood sugar levels and controlling blood insulin levels. Ergo, it can also indirectly help with weight loss.<\/p>\n\n\n\n Research has shown that inositol is safe to take even up to 12-18 grams per day <\/strong>especially when treating various mental health conditions (12, 13). Side effects are mild<\/strong> even at high doses (12-18g); these include gas, headaches, dizziness, tiredness, and nausea.<\/p>\n\n\n\n In point #17, we learned that inositol is used to treat GDM in pregnant women, so it\u2019s safe even for mom-to-be\u2019s. <\/p>\n\n\n\n In the same study quoted earlier (17), the patients were given up to 4g of myo inositol + 400mcg of folic acid daily with no serious side effects reported. <\/p>\n\n\n\n Inositol occurs naturally in breastmilk. In fact, it\u2019s third only to lactose and glucose in terms of concentration. Supplementing with inositol during the breastfeeding journey is generally safe (24<\/a>). But still, we recommend you err on the side of caution. Speak with your doctor first before supplementing with inositol (or any other supplement for that matter).<\/p>\n\n\n\n Many inositol supplements come in convenient powder form, so it\u2019s easy to measure out. You can mix it in water or your favorite drink.<\/p>\n\n\n\n Inositol supplements win in terms of cost-benefit ratio. Inositol has a good safety profile. It\u2019s highly beneficial not just for PCOS women but also for those with other conditions, too. Many studies demonstrate its safety even at high dosage, and even then, side effects are on the minor side of things.<\/p>\n\n\n\n\n
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<\/figure>\n\n\n\n23 Things You Should Know About Inositol<\/h2>\n\n\n\n
1) Inositol helps manage PCOS symptoms<\/h3>\n\n\n\n
2) It improves insulin sensitivity<\/h3>\n\n\n\n
3) Inositol helps improve oocyte or egg quality in women<\/h3>\n\n\n\n
4) It also helps improve sperm quality in men<\/h3>\n\n\n\n
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<\/figure>\n\n\n\n5)\u00a0\u00a0 Improves fertility in PCOS women<\/h3>\n\n\n\n
6)\u00a0\u00a0 Inositol lowers testosterone levels<\/h3>\n\n\n\n
7)\u00a0\u00a0 Inositol will help you get rid of hirsutism, a.k.a. unwanted hair growth<\/h3>\n\n\n\n
8) \u00a0It also helps decrease triglyceride levels<\/h3>\n\n\n\n
9) \u00a0Myo-inositol can lead to lower LDL and total cholesterol levels<\/h3>\n\n\n\n
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<\/figure>\n\n\n\n10) \u00a0Helps clear up your skin<\/h3>\n\n\n\n
11) \u00a0Inositol can help alleviate depression<\/h3>\n\n\n\n
12) \u00a0It may also help relieve anxiety and panic disorders<\/h3>\n\n\n\n
13) \u00a0Myo-inositol is a promising treatment for those with bipolar disorder<\/h3>\n\n\n\n
14) \u00a0May help with psoriasis caused by lithium<\/h3>\n\n\n\n
15) \u00a0Prevents gestational diabetes<\/h3>\n\n\n\n
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<\/figure>\n\n\n\n16) \u00a0May help infants suffering from respiratory distress syndrome<\/h3>\n\n\n\n
17) \u00a0Helps women cope with postmenopausal life<\/h3>\n\n\n\n
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<\/figure>\n\n\n\n18) \u00a0Myo inositol may help women lose weight<\/h3>\n\n\n\n
19) \u00a0Inositol is safe to take even at high doses<\/h3>\n\n\n\n
20) \u00a0It\u2019s even safe for pregnant women<\/h3>\n\n\n\n
21) \u00a0Breastfeeding women may also benefit from supplementing with inositol<\/h3>\n\n\n\n
22) \u00a0Very convenient in powder form<\/h3>\n\n\n\n
23) \u00a0Inositol supplements are relatively affordable<\/h3>\n\n\n\n
Conclusion<\/h2>\n\n\n\n