Jedn\u00edm z nejv\u011bt\u0161\u00edch rizik nepl\u00e1novan\u00e9ho t\u011bhotenstv\u00ed jsou z\u00e1va\u017en\u00e9 vrozen\u00e9 vady, jako jsou defekty neur\u00e1ln\u00ed trubice nebo NTD. P\u0159\u00edkladem je roz\u0161t\u011bp p\u00e1te\u0159e (p\u00e1te\u0159 a m\u00edcha se nevytvo\u0159\u00ed spr\u00e1vn\u011b) a anencefalie (postihuje mozek a lebku). Dobr\u00e9 je, \u017ee t\u011bmto NTD lze p\u0159edch\u00e1zet u\u017e\u00edv\u00e1n\u00edm dostate\u010dn\u00e9ho mno\u017estv\u00ed kyseliny listov\u00e9 p\u0159ed t\u011bhotenstv\u00edm a b\u011bhem n\u011bj. Bohu\u017eel v\u0161ak NTD z\u016fst\u00e1vaj\u00ed probl\u00e9mem v mnoha zem\u00edch sv\u011bta (2<\/a>). <\/p>\n\n\n\n Obohacov\u00e1n\u00ed \u017een v plodn\u00e9m v\u011bku o kyselinu listovou m\u016f\u017ee na\u0161t\u011bst\u00ed zabr\u00e1nit 50-70 % p\u0159\u00edpad\u016f NTD, kter\u00e9 se ka\u017edoro\u010dn\u011b vyskytuj\u00ed. To je v\u00fdznamn\u00e9, proto\u017ee p\u00e9\u010de o d\u00edt\u011b narozen\u00e9 s roz\u0161t\u011bpem p\u00e1te\u0159e nen\u00ed v\u016fbec levn\u00e1 \u2013 celkov\u00e9 p\u0159\u00edm\u00e9 n\u00e1klady na celo\u017eivotn\u00ed p\u00e9\u010di se odhaduj\u00ed na p\u0159ibli\u017en\u011b 792 000 USD (3<\/a>)! <\/p>\n\n\n\n P\u0159itom existuj\u00ed r\u016fzn\u00e9 formy kyseliny listov\u00e9 a fol\u00e1tu – NE v\u0161echny jsou stejn\u00e9! V dal\u0161\u00ed \u010d\u00e1sti se dozv\u00edme, kter\u00e1 forma fol\u00e1tu je pro zdrav\u00ed \u017een v prenat\u00e1ln\u00edm obdob\u00ed nejlep\u0161\u00ed. <\/p>\n\n\n\n Fol\u00e1t, kyselina listov\u00e1 a aktivovan\u00e1 kyselina listov\u00e1 jsou r\u016fzn\u00e9 formy vitaminu B9<\/strong>, vitaminu pot\u0159ebn\u00e9ho pro mnoho d\u016fle\u017eit\u00fdch biologick\u00fdch proces\u016f. Vitamin B9 hraje kl\u00ed\u010dovou roli p\u0159i synt\u00e9ze aminokyselin, tvorb\u011b krve, metabolismu homocysteinu, imunitn\u00edm syst\u00e9mu a d\u011blen\u00ed bun\u011bk. Pom\u00e1h\u00e1 tak\u00e9 p\u0159edch\u00e1zet defekt\u016fm neur\u00e1ln\u00ed trubice u vyv\u00edjej\u00edc\u00edho se plodu(4<\/a>). <\/p>\n\n\n\n Fol\u00e1ty<\/strong> jsou p\u0159irozenou formou vitaminu B9, kter\u00fd je obsa\u017een v cel\u00e9 \u0159ad\u011b potravin, nap\u0159\u00edklad v zelen\u00e9 listov\u00e9 zelenin\u011b, hov\u011bz\u00edch j\u00e1trech, vejc\u00edch, o\u0159e\u0161\u00edch, ovoci a lu\u0161t\u011bnin\u00e1ch. Je biologicky dostupn\u00fd, ale snadno se ni\u010d\u00ed nespr\u00e1vn\u00fdm skladov\u00e1n\u00edm potravin, myt\u00edm a va\u0159en\u00edm(5<\/a>). Fol\u00e1t se p\u0159ed vstupem do krevn\u00edho ob\u011bhu ve st\u0159ev\u011b p\u0159em\u011b\u0148uje na biologicky aktivn\u00ed formu 5-MTHF neboli 5metyltetrahydrofol\u00e1t (6<\/a>). <\/p>\n\n\n\n Kyselina listov\u00e1<\/strong> je syntetick\u00e1 verze fol\u00e1tu. Je stabiln\u011bj\u0161\u00ed ne\u017e kyselina listov\u00e1, a proto je preferovanou formou vitaminu B9, kter\u00e1 se p\u0159id\u00e1v\u00e1 do obohacen\u00fdch potravin, jako jsou sn\u00edda\u0148ov\u00e9 cere\u00e1lie, t\u011bstoviny, chl\u00e9b, mouka a mnoho dopl\u0148k\u016f stravy(5)<\/a>. <\/p>\n\n\n\n S kyselinou listovou je v\u0161ak probl\u00e9m. Ne v\u0161echen se ve st\u0159ev\u011b metabolizuje a p\u0159em\u011b\u0148uje na 5-MTHF jako fol\u00e1ty v potrav\u011b. To m\u016f\u017ee zp\u016fsobit nemetabolizovan\u00e1 kyselina listov\u00e1<\/strong><\/a> hromadit v krvi, co\u017e m\u016f\u017ee v\u00e9st k n\u011bkter\u00fdm zdravotn\u00edm probl\u00e9m\u016fm(7, 8)<\/a>. <\/p>\n\n\n\n T\u00edm se dost\u00e1v\u00e1me k dal\u0161\u00ed generaci syntetick\u00fdch fol\u00e1t\u016f – aktivovan\u00e9 kyselin\u011b listov\u00e9.<\/strong> <\/p>\n\n\n\n Aktivovan\u00e1 kyselina listov\u00e1 (5-MTHF<\/strong> ) je hlavn\u00ed formou fol\u00e1tu, kter\u00e1 se nach\u00e1z\u00ed v krvi. U\u017e\u00edv\u00e1n\u00edm 5-MTHF ji\u017e va\u0161e t\u011blo nemus\u00ed prov\u00e1d\u011bt \u017e\u00e1dn\u00e9 p\u0159em\u011bny. Pro\u010d? Proto\u017ee se ji\u017e jedn\u00e1 o aktivn\u00ed formu 5-MTHF \u2013 formu, na kterou se p\u0159em\u011b\u0148uj\u00ed dietn\u00ed fol\u00e1ty a b\u011b\u017en\u00e1 kyselina listov\u00e1(9)<\/a>. <\/p>\n\n\n\n Aktivovan\u00e1 kyselina listov\u00e1 je vhodnou formou vitaminu B9 nejen pro \u017eeny v prenat\u00e1ln\u00edm obdob\u00ed, ale tak\u00e9 pro osoby s genetickou mutac\u00ed MTHFR. <\/p>\n\n\n\n Zde je infografika, kter\u00e1 popisuje hlavn\u00ed rozd\u00edly mezi t\u011bmito t\u0159emi formami: <\/p>\n\n\n\n Lid\u00e9 s genetickou odchylkou MTHFR, konkr\u00e9tn\u011b s variantami C677T a A1298C, maj\u00ed probl\u00e9my s metabolismem fol\u00e1tu a kyseliny listov\u00e9. Tyto genetick\u00e9 varianty mohou zp\u016fsobovat r\u016fzn\u00e9 zdravotn\u00ed probl\u00e9my, jako je nedostatek vitam\u00edn\u016f (v\u010detn\u011b n\u00edzk\u00e9 hladiny fol\u00e1t\u016f v krvi), vysok\u00e1 hladina homocysteinu (vysok\u00e9 riziko srde\u010dn\u00edch onemocn\u011bn\u00ed), opakovan\u00e9 potraty a d\u011bti s defekty neur\u00e1ln\u00ed trubice(10)<\/a>. <\/p>\n\n\n\n Pokud jste \u017eena, kter\u00e1 se sna\u017e\u00ed ot\u011bhotn\u011bt, a m\u00e1te tuto odchylku MTHFR, mus\u00edte u\u017e\u00edvat aktivovanou kyselinu listovou, aby va\u0161e t\u011blo mohlo tento vitamin pln\u011b vyu\u017e\u00edt. <\/p>\n\n\n\n Existuj\u00ed dva obl\u00edben\u00e9 typy aktivovan\u00e9 kyseliny listov\u00e9: <\/p>\n\n\n\n Pro\u010d je tedy d\u016fle\u017eit\u00e9 rozli\u0161ovat mezi t\u011bmito dv\u011bma formami aktivovan\u00e9 kyseliny listov\u00e9?<\/strong> <\/p>\n\n\n\n Studie z roku 2016 zjistila, \u017ee 5-MTHF z glukosaminov\u00e9 soli se vst\u0159eb\u00e1v\u00e1 1,8kr\u00e1t l\u00e9pe ne\u017e 5-MTHF z v\u00e1penat\u00e9 soli. Byla tak\u00e9 3,1kr\u00e1t biologicky dostupn\u011bj\u0161\u00ed ne\u017e b\u011b\u017en\u00e1 kyselina listov\u00e1 (11)<\/a>. <\/p>\n\n\n\n Aktivovan\u00e1 kyselina listov\u00e1 z glukosaminov\u00e9 soli je d\u00edky sv\u00e9 lep\u0161\u00ed biologick\u00e9 dostupnosti nejlep\u0161\u00ed volbou pro \u017eeny v plodn\u00e9m v\u011bku a pro v\u0161echny, kdo maj\u00ed polymorfismus genu MTHFR.<\/strong> <\/p>\n\n\n\n V na\u0161em Dopl\u0148ky stravy Intelligent Labs 5-MTHF<\/strong><\/a>, pou\u017e\u00edv\u00e1me patentovanou formuli nazvanou Quatrefolic Acid\u00ae, kter\u00e1 je odvozena z glukosaminov\u00e9 soli, kter\u00e1 nen\u00ed z mo\u0159sk\u00fdch kor\u00fd\u0161\u016f, tak\u017ee je vhodn\u00e1 pro konzumaci vegetari\u00e1ny a vegany.\u00a0<\/p>\n\n\n\n Podle studie Obeida a kol. z roku 2013 je aktivovan\u00e1 kyselina listov\u00e1 lep\u0161\u00ed volbou pro t\u011bhotn\u00e9 \u017eeny ne\u017e kyselina listov\u00e1 a b\u011b\u017en\u00e1 kyselina listov\u00e1(12<\/a>). Zde je n\u011bkolik v\u00fdznamn\u00fdch zji\u0161t\u011bn\u00ed z jejich v\u00fdzkumu: <\/p>\n\n\n\n Podle CDC<\/a> je zapot\u0159eb\u00ed “n\u011bkolik m\u011bs\u00edc\u016f pravideln\u00e9 konzumace fol\u00e1t\u016f, aby se dos\u00e1hlo dostate\u010dn\u011b vysok\u00e9 koncentrace fol\u00e1t\u016f v krvi pro prevenci NTD”. <\/p>\n\n\n\n To znamen\u00e1, \u017ee \u017eeny by m\u011bly za\u010d\u00edt u\u017e\u00edvat 5-MTHF z glukosaminov\u00e9 soli n\u011bkolik m\u011bs\u00edc\u016f p\u0159ed po\u010det\u00edm a\u017e do prvn\u00edho trimestru t\u011bhot<\/strong> enstv\u00ed, proto\u017ee v tomto obdob\u00ed maj\u00ed vy\u0161\u0161\u00ed pot\u0159ebu fol\u00e1t\u016f. <\/p>\n\n\n\n Fol\u00e1ty jsou z\u00e1sadn\u00ed pro r\u016fst a v\u00fdvoj plodu. Dostatkem fol\u00e1t\u016f p\u0159ed po\u010det\u00edm lze p\u0159edej\u00edt NTD, proto je d\u016fle\u017eit\u00e9, aby maminky dok\u00e1zaly pln\u011b vyu\u017e\u00edt fol\u00e1ty, kter\u00e9 p\u0159ij\u00edmaj\u00ed (13)<\/a>. <\/p>\n\n\n\n Tot\u00e9\u017e plat\u00ed i pro otce. Mu\u017ei tak\u00e9 pot\u0159ebuj\u00ed dostate\u010dnou hladinu fol\u00e1t\u016f, aby si zajistili \u00fasp\u011b\u0161n\u00e9 t\u011bhotenstv\u00ed. P\u0159e\u010dt\u011bte si tento \u010dl\u00e1nek, abyste se dozv\u011bd\u011bli v\u00edce o v\u00fdhody kyseliny listov\u00e9 pro mu\u017ee<\/strong><\/a>.\u00a0<\/p>\n\n\n\n Pou\u017eit\u00ed spr\u00e1vn\u00e9 formy fol\u00e1tu – v tomto p\u0159\u00edpad\u011b aktivovan\u00e9 kyseliny listov\u00e9 \u2013 je d\u016fle\u017eit\u00e9 nejen pro prenat\u00e1ln\u00ed zdrav\u00ed, ale tak\u00e9 pro ty, kte\u0159\u00ed maj\u00ed probl\u00e9my s metabolismem fol\u00e1tu a kyseliny listov\u00e9 ve strav\u011b. Vysok\u00e1 biologick\u00e1 dostupnost 5-MTHF znamen\u00e1, \u017ee m\u016f\u017eete vyu\u017e\u00edt v\u0161ech \u00fa\u017easn\u00fdch zdravotn\u00edch p\u0159\u00ednos\u016f fol\u00e1tu (p\u0159e\u010dt\u011bte si n\u00e1\u0161 \u010dl\u00e1nek pr\u016fvodce fol\u00e1ty a methylfol\u00e1tem 5-MTHF<\/strong><\/a> zde pro v\u00edce informac\u00ed).\u00a0<\/p>\n\n\n\n Co se t\u00fd\u010de nejlep\u0161\u00edho dopl\u0148ku 5-MTHF pro t\u011bhotenstv\u00ed? Pod\u00edvejte se na na\u0161e 1MG 5-MTHF<\/strong><\/a> a 5MG 5-MTHF<\/strong><\/a> v obchod\u011b Intelligent Labs.\u00a0<\/p>\n\n\n\n\n 1) Bearak, Jonathan, et al. \u201cUnintended Pregnancy and Abortion by Income, Region, and the Legal Status of Abortion: Estimates from a Comprehensive Model for 1990\u20132019.\u201d The Lancet Global Health, vol. 8, no. 9, 2020, pp. e1152\u201361. Crossref, https:\/\/doi.org\/10.1016\/s2214-109x(20)30315-6.<\/p>\n\n\n\n 2) \u201cKey Findings: Global Burden of Neural Tube Defects.\u201d Centers for Disease Control and Prevention, 25 Sept. 2018, www.cdc.gov\/ncbddd\/birthdefectscount\/features\/kf-neutral-tube-defects-burden.html.<\/p>\n\n\n\n 3) \u201cData and Statistics.\u201d Centers for Disease Control and Prevention, 24 Sept. 2018, www.cdc.gov\/ncbddd\/birthdefectscount\/data.html#:%7E:text=In%20the%20United%20States%2C%203%2C000,defects%20each%20year%20(3).<\/p>\n\n\n\n 4) \u201cEU Register of Nutrition and Health Claims Made on Foods (v.3.6).\u201d European Commission Food Safety, ec.europa.eu\/food\/safety\/labelling_nutrition\/claims\/register\/public\/?event=search. Accessed 21 Mar. 2022.<\/p>\n\n\n\n 5) \u201cGeneral Information About NTDs, Folic Acid, and Folate.\u201d Centers for Disease Control and Prevention, 8 July 2021, www.cdc.gov\/ncbddd\/folicacid\/faqs\/faqs-general-info.html.<\/p>\n\n\n\n 6) Alpers, David H. \u201cAbsorption and blood\/cellular transport of folate and cobalamin: Pharmacokinetic and physiological considerations.\u201d Biochimie vol. 126 (2016): 52-6. doi:10.1016\/j.biochi.2015.11.006<\/p>\n\n\n\n 7) Valera-Gran, Desir\u00e9e et al. \u201cEffect of maternal high dosages of folic acid supplements on neurocognitive development in children at 4-5 y of age: the prospective birth cohort Infancia y Medio Ambiente (INMA) study.\u201d The American journal of clinical nutrition vol. 106,3 (2017): 878-887. doi:10.3945\/ajcn.117.152769<\/p>\n\n\n\n 8) Plumptre, Lesley et al. \u201cHigh concentrations of folate and unmetabolized folic acid in a cohort of pregnant Canadian women and umbilical cord blood.\u201d The American journal of clinical nutrition vol. 102,4 (2015): 848-57. doi:10.3945\/ajcn.115.110783<\/p>\n\n\n\n 9) Scaglione, Francesco, and Giscardo Panzavolta. \u201cFolate, folic acid and 5-methyltetrahydrofolate are not the same thing.\u201d Xenobiotica; the fate of foreign compounds in biological systems vol. 44,5 (2014): 480-8. doi:10.3109\/00498254.2013.845705<\/p>\n\n\n\n 10) \u201cMTHFR Gene Variant | Genetic and Rare Diseases Information Center (GARD) \u2013 an NCATS Program.\u201d NIH GARD, rarediseases.info.nih.gov\/diseases\/10953\/mthfr-gene-variant. Accessed 21 Mar. 2022.<\/p>\n\n\n\n 11) Miraglia, Niccol\u00f2 et al. \u201cEnhanced oral bioavailability of a novel folate salt: comparison with folic acid and a calcium folate salt in a pharmacokinetic study in rats.\u201d Minerva ginecologica vol. 68,2 (2016): 99-105.<\/p>\n\n\n\n 12) Obeid, Rima, Holzgreve, Wolfgang and Pietrzik, Klaus. \u201cIs 5-methyltetrahydrofolate an alternative to folic acid for the prevention of neural tube defects?\u201d Journal of Perinatal Medicine, vol. 41, no. 5, 2013, pp. 469-483. https:\/\/doi.org\/10.1515\/jpm-2012-0256<\/p>\n\n\n\n 13) Ferrazzi, Enrico et al. \u201cFolic acid versus 5- methyl tetrahydrofolate supplementation in pregnancy.\u201d European journal of obstetrics, gynecology, and reproductive biology vol. 253 (2020): 312-319. doi:10.1016\/j.ejogrb.2020.06.012<\/p>\n\n\n\n<\/details>\n\n<\/div>\n \n<\/div>\n\n\n\n\n <\/p>\n","protected":false},"excerpt":{"rendered":" Zodpov\u011bdn\u00e9 rodi\u010dovstv\u00ed za\u010d\u00edn\u00e1 ji\u017e dlouho p\u0159ed narozen\u00edm d\u00edt\u011bte. P\u0159ijet\u00ed ur\u010dit\u00fdch opat\u0159en\u00ed, jako je vyv\u00e1\u017een\u00e1 strava, cvi\u010den\u00ed a u\u017e\u00edv\u00e1n\u00ed prenat\u00e1ln\u00edch vitam\u00edn\u016f, pom\u00e1h\u00e1 zv\u00fd\u0161it \u0161ance na zdrav\u00e9 t\u011bhotenstv\u00ed. V tomto p\u0159\u00edsp\u011bvku se budeme v\u011bnovat jednomu z nejd\u016fle\u017eit\u011bj\u0161\u00edch vitamin\u016f, kter\u00fd m\u016f\u017ee nast\u00e1vaj\u00edc\u00ed maminka u\u017e\u00edvat, a to aktivovan\u00e9 kyselin\u011b listov\u00e9. Pro\u010d u\u017e\u00edvat kyselinu listovou pro po\u010det\u00ed a t\u011bhotenstv\u00ed? Pro…<\/p>\n","protected":false},"author":2,"featured_media":129329,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","footnotes":""},"categories":[2621],"tags":[2623],"coauthors":[],"class_list":["post-221612","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-vyziva","tag-5-mthf"],"taxonomy_info":{"category":[{"value":2621,"label":"V\u00fd\u017eiva"}],"post_tag":[{"value":2623,"label":"5-MTHF"}]},"featured_image_src_large":["https:\/\/eu.intelligentlabs.org\/wp-content\/uploads\/2022\/03\/5-mthf-activated-folic-acid-for-prenatal-health-01-1024x512.jpg",1024,512,true],"author_info":{"display_name":"David Pashley","author_link":"https:\/\/eu.intelligentlabs.org\/cs-cz\/author\/david\/"},"comment_info":0,"category_info":[{"term_id":2621,"name":"V\u00fd\u017eiva","slug":"vyziva","term_group":0,"term_taxonomy_id":2621,"taxonomy":"category","description":"","parent":0,"count":61,"filter":"raw","cat_ID":2621,"category_count":61,"category_description":"","cat_name":"V\u00fd\u017eiva","category_nicename":"vyziva","category_parent":0}],"tag_info":[{"term_id":2623,"name":"5-MTHF","slug":"5-mthf","term_group":0,"term_taxonomy_id":2623,"taxonomy":"post_tag","description":"","parent":0,"count":3,"filter":"raw"}],"wpml":{"language":"cs-cz","is_original":false,"original_post_id":130686,"translations":{"cs-cz":{"id":221612,"language":"cs-cz","is_original":false},"de-at":{"id":169259,"language":"de-at","is_original":false},"de-de":{"id":75417,"language":"de-de","is_original":false},"en-gb":{"id":130686,"language":"en-gb","is_original":true},"en-ie":{"id":164126,"language":"en-ie","is_original":false},"en-mt":{"id":165499,"language":"en-mt","is_original":false},"es-es":{"id":74994,"language":"es-es","is_original":false},"et-ee":{"id":230258,"language":"et-ee","is_original":false},"fr-fr":{"id":129328,"language":"fr-fr","is_original":false},"hu-hu":{"id":225136,"language":"hu-hu","is_original":false},"it-it":{"id":75244,"language":"it-it","is_original":false},"lt-lt":{"id":237153,"language":"lt-lt","is_original":false},"lv-lv":{"id":230629,"language":"lv-lv","is_original":false},"nl-nl":{"id":175346,"language":"nl-nl","is_original":false},"pt-pt":{"id":168951,"language":"pt-pt","is_original":false},"ro-ro":{"id":253675,"language":"ro-ro","is_original":false},"sl-si":{"id":239024,"language":"sl-si","is_original":false}}},"_links":{"self":[{"href":"https:\/\/eu.intelligentlabs.org\/cs-cz\/wp-json\/wp\/v2\/posts\/221612","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/eu.intelligentlabs.org\/cs-cz\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/eu.intelligentlabs.org\/cs-cz\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/eu.intelligentlabs.org\/cs-cz\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/eu.intelligentlabs.org\/cs-cz\/wp-json\/wp\/v2\/comments?post=221612"}],"version-history":[{"count":1,"href":"https:\/\/eu.intelligentlabs.org\/cs-cz\/wp-json\/wp\/v2\/posts\/221612\/revisions"}],"predecessor-version":[{"id":251816,"href":"https:\/\/eu.intelligentlabs.org\/cs-cz\/wp-json\/wp\/v2\/posts\/221612\/revisions\/251816"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/eu.intelligentlabs.org\/cs-cz\/wp-json\/wp\/v2\/media\/129329"}],"wp:attachment":[{"href":"https:\/\/eu.intelligentlabs.org\/cs-cz\/wp-json\/wp\/v2\/media?parent=221612"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/eu.intelligentlabs.org\/cs-cz\/wp-json\/wp\/v2\/categories?post=221612"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/eu.intelligentlabs.org\/cs-cz\/wp-json\/wp\/v2\/tags?post=221612"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/eu.intelligentlabs.org\/cs-cz\/wp-json\/wp\/v2\/coauthors?post=221612"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}![\"aktivovan\u00e1](\"https:\/\/eu.intelligentlabs.org\/wp-content\/uploads\/2025\/08\/image-25-1024x512.jpeg\")
<\/figure>\n\n\n\nR\u016fzn\u00e9 formy kyseliny listov\u00e9 \u2013 a pro\u010d je aktivovan\u00e1 kyselina listov\u00e1 nejlep\u0161\u00ed formou pro podporu prenat\u00e1ln\u00edho zdrav\u00ed <\/h2>\n\n\n\n
Rozd\u00edly mezi fol\u00e1ty, kyselinou listovou a aktivovanou kyselinou listovou <\/h3>\n\n\n\n
![\"r\u016fzn\u00e9](\"https:\/\/eu.intelligentlabs.org\/wp-content\/uploads\/2025\/08\/image-9-492x1024.png\")
<\/figure>\n\n\n\nJak m\u016f\u017ee 5-MTHF pomoci \u017een\u00e1m (a mu\u017e\u016fm) s polymorfismem genu MTHFR <\/h3>\n\n\n\n
![\"dopln\u011bk](\"https:\/\/eu.intelligentlabs.org\/wp-content\/uploads\/2025\/09\/image-01-36.jpeg\")
<\/figure>\n\n\n\nJak\u00e9 jsou dal\u0161\u00ed v\u00fdhody kyseliny listov\u00e9 aktivovan\u00e9 5-MTHF? <\/h2>\n\n\n\n
Kdy je nejlep\u0161\u00ed za\u010d\u00edt u\u017e\u00edvat aktivovanou kyselinu listovou v t\u011bhotenstv\u00ed? <\/h2>\n\n\n\n
Z\u00e1v\u011bre\u010dn\u00e1 slova <\/h2>\n\n\n\n
Reference<\/summary>\n\n