{"id":221187,"date":"2024-07-30T02:21:58","date_gmt":"2024-07-30T01:21:58","guid":{"rendered":"https:\/\/eu.intelligentlabs.org\/je-horcik-dobry-pro-mozek\/"},"modified":"2025-09-23T11:44:24","modified_gmt":"2025-09-23T10:44:24","slug":"je-horcik-dobry-pro-mozek","status":"publish","type":"post","link":"https:\/\/eu.intelligentlabs.org\/cs-cz\/je-horcik-dobry-pro-mozek\/","title":{"rendered":"Je ho\u0159\u010d\u00edk dobr\u00fd pro mozek?"},"content":{"rendered":"\n\n\n

Existuje n\u011bco jako kouzeln\u00e1 pilulka, kter\u00e1 dok\u00e1\u017ee zlep\u0161it v\u00e1\u0161 mozek? M\u016f\u017ee b\u00fdt ho\u0159\u010d\u00edk skute\u010dn\u011b odpov\u011bd\u00ed na zv\u00fd\u0161en\u00ed v\u00fdkonu mozku? Jak moc je ho\u0159\u010d\u00edk dobr\u00fd pro mozek? Vezmete si pilulku a zv\u00fd\u0161\u00ed se v\u00e1m mozkov\u00e1 kapacita? <\/p>\n\n\n\n

Hmm, vid\u011bl jsem Limitless<\/em>, ale to byl jen film, ne? Takov\u00e9 v\u011bci se ve skute\u010dn\u00e9m sv\u011bt\u011b ned\u011bj\u00ed! Nebo ano? <\/p>\n\n\n\n

Nen\u00ed \u017e\u00e1dn\u00fdm tajemstv\u00edm, \u017ee ho\u0159\u010d\u00edk je \u017eivotn\u011b d\u016fle\u017eitou \u017eivinou<\/a>. V t\u011ble se pod\u00edl\u00ed na v\u00edce ne\u017e 600 biochemick\u00fdch funkc\u00edch, je obsa\u017een v kostech, pom\u00e1h\u00e1 produkovat energii a b\u00edlkoviny a udr\u017euje srdce v chodu (1). V\u00fdzkum nyn\u00ed tak\u00e9 ukazuje, \u017ee ho\u0159\u010d\u00edk zlep\u0161uje pam\u011b\u0165 a schopnost u\u010den\u00ed. Je\u0161t\u011b d\u016fle\u017eit\u011bj\u0161\u00ed je, \u017ee p\u0159i nedostatku ho\u0159\u010d\u00edku v mozku m\u016f\u017ee doj\u00edt k v\u00fdrazn\u00e9mu zhor\u0161en\u00ed pam\u011bti a schopnosti u\u010den\u00ed (2).\u00a0<\/p>\n\n\n\n

\"ho\u0159\u010d\u00edk<\/figure>\n\n\n\n

Plasticita mozku a u\u010den\u00ed <\/h2>\n\n\n\n

Kl\u00ed\u010dovou roli v na\u0161\u00ed schopnosti u\u010dit se a pou\u017e\u00edvat pam\u011b\u0165 hraje schopnost mozku vytv\u00e1\u0159et spojen\u00ed mezi sv\u00fdmi neurony<\/strong> (bu\u0148kami, kter\u00e9 p\u0159en\u00e1\u0161ej\u00ed sign\u00e1ly v mozku a nervov\u00e9m syst\u00e9mu). <\/p>\n\n\n\n

Tento proces se ozna\u010duje jako “plasticita mozku<\/strong>” a \u010d\u00edm rychleji to mozek dok\u00e1\u017ee nebo \u010d\u00edm je “plasti\u010dt\u011bj\u0161\u00ed”, t\u00edm snadn\u011bji se m\u016f\u017eeme u\u010dit, myslet, zapamatovat si, vytv\u00e1\u0159et pozitivn\u00ed vzorce chov\u00e1n\u00ed a opou\u0161t\u011bt ty negativn\u00ed. <\/p>\n\n\n\n

V\u00fdzkum vlivu ho\u0159\u010d\u00edku na plasticitu mozku<\/strong> za\u010dal, kdy\u017e v\u011bdci zkoumali r\u016fst mozkov\u00fdch bun\u011bk v Petriho misce a zjistili, \u017ee mozkov\u00e9 bu\u0148ky se l\u00e9pe spojuj\u00ed a rostou v p\u0159\u00edtomnosti ho\u0159\u010d\u00edku. <\/p>\n\n\n\n

Nejlep\u0161\u00ed forma dopl\u0148k\u016f ho\u0159\u010d\u00edku je…? <\/h2>\n\n\n\n

Krom\u011b toho, \u017ee ho\u0159\u010d\u00edk z\u00edsk\u00e1v\u00e1me ze stravy<\/strong>, m\u016f\u017eeme jeho hladinu v t\u011ble zv\u00fd\u0161it tak\u00e9 peror\u00e1ln\u00edm u\u017e\u00edv\u00e1n\u00edm dopl\u0148k\u016f stravy nebo jeho nitro\u017eiln\u00edm pod\u00e1v\u00e1n\u00edm. <\/p>\n\n\n\n

Intraven\u00f3zn\u00ed pod\u00e1v\u00e1n\u00ed ho\u0159\u010d\u00edku v\u0161ak nen\u00ed praktick\u00fdm \u0159e\u0161en\u00edm. <\/p>\n\n\n\n

Standardn\u00ed peror\u00e1ln\u00ed dopl\u0148ky ho\u0159\u010d\u00edku nav\u00edc nedok\u00e1\u017eou p\u0159ekonat hematoencefalickou bari\u00e9ru (polopropustn\u00e1 ochrann\u00e1 membr\u00e1nov\u00e1 bari\u00e9ra, kter\u00e1 odd\u011bluje cirkuluj\u00edc\u00ed krev v t\u011ble od mozkov\u00e9 tekutiny), a proto nejsou schopny zv\u00fd\u0161it hladinu ho\u0159\u010d\u00edku v mozku. Skupina mezin\u00e1rodn\u00edch v\u011bdc\u016f z MIT, Tsinghua University (Peking) a University of Toronto vyvinula nov\u00fd typ ho\u0159\u010d\u00edku<\/strong> – Magnesium-L-Threonate<\/strong><\/a> (MgT<\/strong>), kter\u00fd byl speci\u00e1ln\u011b navr\u017een tak, aby byl schopen proch\u00e1zet hematoencefalickou bari\u00e9rou<\/strong>, mohl b\u00fdt u\u017e\u00edv\u00e1n ve form\u011b kapsl\u00ed a \u00fa\u010dinn\u011b zvy\u0161oval hladinu ho\u0159\u010d\u00edku v mozku.  <\/p>\n\n\n\n

\"hodnocen\u00ed<\/figure>\n\n\n\n
\"Laboratorn\u00ed<\/figure>\n\n\n\n

Nejprve testovali MgT na potkanech a podrobili je s\u00e9rii test\u016f zam\u011b\u0159en\u00fdch na jejich schopnost u\u010den\u00ed a pam\u011b\u0165. V\u00fdsledky uk\u00e1zaly, \u017ee MgT nejen zlep\u0161il schopnost potkan\u016f u\u010dit se, ale tak\u00e9 zlep\u0161il jejich pracovn\u00ed pam\u011b\u0165 a kr\u00e1tkodobou a dlouhodobou pam\u011b\u0165 u mlad\u00fdch i star\u0161\u00edch potkan\u016f (3).  <\/p>\n\n\n\n

Jak tedy funguje L-treon\u00e1t ho\u0159e\u010dnat\u00fd?<\/strong> <\/h2>\n\n\n\n

Ho\u0159\u010d\u00edk vis\u00ed na NMDA receptoru, kter\u00fd je nezbytn\u00fd pro u\u010den\u00ed a nach\u00e1z\u00ed se v meze\u0159e (synaps\u00edch) mezi nervov\u00fdmi bu\u0148kami (neurony). <\/p>\n\n\n\n

\"nmda<\/figure><\/div>\n\n\n\n

Receptor NMDA je aktivov\u00e1n neurotransmiterem glutam\u00e1tem a umo\u017e\u0148uje pr\u016ftok v\u00e1pn\u00edku kan\u00e1lem – aktivaci\/pos\u00edl\u00e1n\u00ed elektrick\u00fdch sign\u00e1l\u016f mezi neurony. <\/p>\n\n\n\n

Ho\u0159\u010d\u00edk m\u016f\u017ee zabr\u00e1nit glutam\u00e1tu v aktivaci NMDA receptoru, \u010d\u00edm\u017e “zav\u0159e dve\u0159e” a nepropust\u00ed v\u00e1pn\u00edk kan\u00e1lem, v podstat\u011b funguje jako “hl\u00edda\u010d”. Ho\u0159\u010d\u00edk v podstat\u011b br\u00e1n\u00ed aktivaci t\u011bchto receptor\u016f p\u0159\u00edli\u0161 velk\u00fdm mno\u017estv\u00edm glutam\u00e1tu, aby nedoch\u00e1zelo k nadm\u011brn\u00e9 stimulaci neuronu. <\/p>\n\n\n\n

Kdy\u017e jsou bu\u0148ky nadm\u011brn\u011b stimulov\u00e1ny, nevyst\u0159eluj\u00ed sv\u00e9 impulzy norm\u00e1ln\u011b a elektrick\u00e9 sign\u00e1ly nebo spojen\u00ed, kter\u00e1 se sna\u017e\u00ed vytvo\u0159it, jsou \u010dasto ne\u00fasp\u011b\u0161n\u00e9. P\u0159edstavte si obrovsk\u00fd dav lid\u00ed, kte\u0159\u00ed se v\u0161ichni najednou sna\u017e\u00ed protla\u010dit turniketem, prost\u011b to nejde. Nedostatek ho\u0159\u010d\u00edku \/ bez ho\u0159\u010d\u00edku p\u016fsob\u00edc\u00edho jako ochrana m\u016f\u017ee nav\u00edc v\u00e9st k dlouhodob\u00e9 nadm\u011brn\u00e9 stimulaci, kter\u00e1 m\u016f\u017ee po\u0161kodit nervov\u00e9 bu\u0148ky a v d\u016fsledku toho zp\u016fsobit probl\u00e9my s u\u010den\u00edm a pam\u011bt\u00ed v dlouhodob\u00e9m horizontu (4). <\/p>\n\n\n\n

Pro\u010d m\u00e1me nedostatek ho\u0159\u010d\u00edku?<\/strong> <\/h2>\n\n\n\n

Jedn\u00edm z velk\u00fdch probl\u00e9m\u016f je, \u017ee ho\u0159\u010d\u00edk je dnes v na\u0161\u00ed strav\u011b mnohem h\u016f\u0159e dostupn\u00fd, ne\u017e tomu bylo po v\u011bt\u0161inu na\u0161eho v\u00fdvoje. <\/p>\n\n\n\n

Mnoz\u00ed z n\u00e1s se od zdrav\u00fdch a v\u00fd\u017eivn\u00fdch potravin p\u0159esunuli ke zpracovan\u00fdm potravin\u00e1m bez ho\u0159\u010d\u00edku a dal\u0161\u00edch \u017eivin. Tak\u00e9 v zem\u011bd\u011blstv\u00ed, kde vyv\u00edj\u00edme rychleji rostouc\u00ed odr\u016fdy, abychom zv\u00fd\u0161ili v\u00fdnosy plodin, maj\u00ed ovoce a zelenina v p\u016fd\u011b m\u00e9n\u011b \u010dasu na vst\u0159eb\u00e1v\u00e1n\u00ed \u017eivin z p\u016fdy. I ty dobr\u00e9 potraviny, kter\u00e9 dnes j\u00edme, jsou m\u00e9n\u011b kvalitn\u00ed ne\u017e p\u0159ed 30 lety, kdy jejich p\u011bstov\u00e1n\u00ed trvalo d\u00e9le (5). <\/p>\n\n\n\n

Krom\u011b toho se dnes s\u016fl b\u011bl\u00ed na b\u00edlo, \u010d\u00edm\u017e se odstra\u0148uje ho\u0159\u010d\u00edk. Naproti tomu plnospektr\u00e1ln\u00ed soli, jako je keltsk\u00e1 mo\u0159sk\u00e1 s\u016fl nebo r\u016f\u017eov\u00e1 him\u00e1lajsk\u00e1 s\u016fl, obsahuj\u00ed ho\u0159\u010d\u00edk (kter\u00fd konzumovali na\u0161i p\u0159edkov\u00e9). Dokonce i z na\u0161\u00ed pitn\u00e9 vody byl odstran\u011bn ho\u0159\u010d\u00edk, kter\u00fd je obsa\u017een v miner\u00e1ln\u00ed vod\u011b. Dal\u0161\u00edm v\u00fdznamn\u00fdm probl\u00e9mem je tempo a stres na\u0161eho modern\u00edho sv\u011bta. Stres vy\u010derp\u00e1v\u00e1 ho\u0159\u010d\u00edk z na\u0161eho t\u011bla. Vzhledem k tomu nen\u00ed p\u0159ekvapiv\u00e9, \u017ee 80 % lid\u00ed trp\u00ed nedostatkem ho\u0159\u010d\u00edku. <\/p>\n\n\n\n

\u0158e\u0161en\u00ed nedostatku ho\u0159\u010d\u00edku?<\/strong> <\/h2>\n\n\n\n

Ve spole\u010dnosti Intelligent Labs jsme vytvo\u0159ili n\u011bco, co pova\u017eujeme za kompletn\u00ed dopln\u011bk ho\u0159\u010d\u00edku<\/a>. Kombinuje t\u0159i r\u016fzn\u00e9 druhy ho\u0159\u010d\u00edku.\u00a0<\/p>\n\n\n\n